Food Habits of Dabbling Ducks During Fall Migration in a Prairie Pothole System, Heron Lake, Minnesota

We conducted an analysis of dabbling duck food habits in the fall of 2002 and 2003 in the Heron Lake system. Gizzard contents of hunter-harvested birds were analyzed using the percent aggregate volume method to determine what food items were consumed and in what quantity. Curltop Ladysthumb (Polygonum lapathifolium) was the food item consumed most often (82.2%) and in the greatest volume (34.2 ml). Sago Pondweed (Stuckenia pectinata) was the only food item of which multiple plant parts were consumed. However, the seeds and tubers only comprised 1.27 and 0.07 of the total aggregate percent

Tau and atrophy: domain-specific relationships with cognition.

BackgroundLate-onset Alzheimer's disease (AD) is characterized by primary memory impairment, which then progresses towards severe deficits across cognitive domains. Here, we report how performance in cognitive domains relates to patterns of tau deposition and cortical thickness.MethodsWe analyzed data from 131 amyloid-β positive participants (55 cognitively normal, 46 mild cognitive impairment, 30 AD) of the Alzheimer's Disease Neuroimaging Initiative who underwent magnetic resonance imaging (MRI), flortaucipir (FTP) positron emission tomography, and neuropsychological testing. Surface-based vertex-wise and region-of-interest analyses were conducted between FTP and cognitive test scores, and between cortical thickness and cognitive test scores.ResultsFTP and thickness were differentially related to cognitive performance in several domains. FTP-cognition associations were more widespread than thickness-cognition associations. Further, FTP-cognition patterns reflected cortical systems that underlie different aspects of cognition.ConclusionsOur findings indicate that AD-related decline in domain-specific cognitive performance reflects underlying progression of tau and atrophy into associated brain circuits. They also suggest that tau-PET may have better sensitivity to this decline than MRI-derived measures of cortical thickness

Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau.

In this study, we aimed to assess whether women are able to withstand more tau before exhibiting verbal memory impairment. Using data from 121 amyloid-β-positive Alzheimer's Disease Neuroimaging Initiative participants, we fit a linear model with Rey Auditory Verbal Learning Test score as the response variable and tau-PET standard uptake value ratio as the predictor and took the residuals as an estimate of verbal memory reserve for each subject. Women demonstrated higher reserve (i.e. residuals), whether the Learning (t = 2.78, P = 0.006) or Delay (t = 2.14, P = 0.03) score from the Rey Auditory Verbal Learning Test was used as a measure of verbal memory ability. To validate these findings, we examined 662 National Alzheimer's Coordinating Center participants with a C2/C3 score (Consortium to Establish a Registry for Alzheimer's Disease) at autopsy. We stratified our National Alzheimer's Coordinating Center sample into Braak 1/2, Braak 3/4 and Braak 5/6 subgroups. Within each subgroup, we compared Logical Memory scores between men and women. Men had worse verbal memory scores within the Braak 1/2 (Logical Memory Immediate: β = -5.960 ± 1.517, P < 0.001, Logical Memory Delay: β = -5.703 ± 1.677, P = 0.002) and Braak 3/4 (Logical Memory Immediate: β = -2.900 ± 0.938, P = 0.002, Logical Memory Delay: β = -2.672 ± 0.955, P = 0.006) subgroups. There were no sex differences in Logical Memory performance within the Braak 5/6 subgroup (Logical Memory Immediate: β = -0.314 ± 0.328, P = 0.34, Logical Memory Delay: β = -0.195 ± 0.287, P = 0.50). Taken together, our results point to a sex-related verbal memory reserve

From Newton's Laws to the Wheeler-DeWitt Equation

This is a pedagogical paper which explains some ideas in cosmology at a level accessible to undergraduate students. It does not use general relativity, but uses the ideas of Newtonian cosmology worked out by Milne and McCrea. The cosmological constant is also introduced within a Newtonian framework. Following standard quantization procedures the Wheeler-DeWitt equation in the minisuperspace approximation is derived for empty and non-empty universes.Comment: 13 pages, 1 figur

Nasal Glioma: Prenatal Diagnosis and Multidisciplinary Surgical Approach

Nasal gliomas are congenital, nonmalignant rests of neuroglial tissue that typically present as a craniofacial mass. The differential diagnosis of such masses includes lesions that often require the involvement of various surgical subspecialties, including otolaryngology, neurosurgery, plastic surgery, and ophthalmology. Early surgical excision of these masses is advised to minimize nasal and craniofacial distortion. Accordingly, early diagnosis and management planning are paramount, and advances in prenatal imaging are creating a new role for obstetricians and radiologists in the initiation of diagnostic and therapeutic interventions. We describe the case history of a young patient found to have a craniofacial mass on routine prenatal ultrasound and subsequently managed with a multidisciplinary team approach

Estimating the Porosity of the Interstellar Medium from Three-Dimensional Photoionization Modeling of H II Regions

We apply our three dimensional photoionization code to model Wisconsin H-alpha Mapper observations of the H II region surrounding the O9.5V star Zeta Oph. Our models investigate the porosity of the interstellar medium around zeta Oph and the effects of 3D densities on the H-alpha surface brightness and variation in the [N II]/H-alpha line ratio. The Zeta Oph H II region has a well characterized ionizing source, so it is an excellent starting point for 3D models of diffuse ionized gas. We investigate various hierarchically clumped density structures, varying the overall smoothness within the clumping algorithm. By simulating the observations, we can estimate the porosity of the medium in the vicinity of Zeta Oph and find that within the context of our hierarchically clumped models, around 50% to 80% of the volume is occupied by clumps surrounded by a low density smooth medium. We also conclude that in order for O stars to ionize the diffuse Warm Ionized Medium, the O star environment must be more porous than that surrounding Zeta Oph, with clumps occupying less than one half of the interstellar volume. Our clumpy models have irregular boundaries, similar to observed H II regions. However, in observed H II regions it is difficult to identify the precise location of the boundary because of the foreground and/or background emission from the widespread Warm Ionized Medium. This complicates the interpretation of the predicted rapid rise of some emission line ratios near the edge of uniform density H II regions and combined with the three dimensional clumpy nature of the interstellar medium may explain the apparent lack of distinctive emission line ratios near H I -- H II interfaces.Comment: Accepted for publication in Ap

Toward scalable biocatalytic conversion of 5-hydroxymethylfurfural by galactose oxidase using coordinated reaction and enzyme engineering

5-Hydroxymethylfurfural (HMF) can be transformed to a range of industrially useful derivatives, such as 2,5-diformylfuran (DFF), but the reactions needed for efficient industrial production are hindered by several issues. Here, the authors perform reaction and enzyme engineering resulting in a galactose oxidase variant with high activity towards HMF, improved oxygen binding and high productivity

Crew Exploration Vehicle Ascent Abort Overview

One of the primary design drivers for NASA's Crew Exploration Vehicle (CEV) is to ensure crew safety. Aborts during the critical ascent flight phase require the design and operation of CEV systems to escape from the Crew Launch Vehicle and return the crew safely to the Earth. To accomplish this requirement of continuous abort coverage, CEV ascent abort modes are being designed and analyzed to accommodate the velocity, altitude, atmospheric, and vehicle configuration changes that occur during ascent. The analysis involves an evaluation of the feasibility and survivability of each abort mode and an assessment of the abort mode coverage. These studies and design trades are being conducted so that more informed decisions can be made regarding the vehicle abort requirements, design, and operation. This paper presents an overview of the CEV, driving requirements for abort scenarios, and an overview of current ascent abort modes. Example analysis results are then discussed. Finally, future areas for abort analysis are addressed

Gamma oscillations correlate with working memory load in humans

Functional imaging of human cortex implicates a diverse network of brain regions supporting working memory—the capacity to hold and manipulate information for short periods of time. Although we are beginning to map out the brain networks supporting working memory, little is known about its physiological basis. We analyzed intracranial recordings from two epileptic patients as they performed a working memory task. Spectral analyses revealed that, in both patients, gamma (30-60 Hz) oscillations increased approximately linearly with memory load, tracking closely with memory load over the course of the trial. This constitutes the first evidence that gamma oscillations, widely implicated in perceptual processes, support the maintenance of multiple items in working memory